Abstract
Internal Root Resorption is usually asymptomatic. Manifest itself under pathologic conditions and requires vital pulp tissue for their development. Etiologic factors such as trauma, inflammation, caries, restorative procedures have been suggested.
Highlights
Broomell in 1898, was the first person in using the term “resorption” [1]
As stated by the Glossary of the American Association of Endodontists, internal resorption is defined as an inflammatory process initiated within the pulp space with loss of dentin and possible invasion of the cementum [2]
Multinuclear odontoclast cells involved in internal inflammatory root resorption are equivalent to bone resorbing osteoclasts
Summary
Broomell in 1898, was the first person in using the term “resorption” [1]. Firstly described as osteoclasts, they are able to resorb mineralized dental tissues, where they are called odontoclasts [11] They are situated in dental pulp and periodontal ligament, sharing structural and cytochemical properties similarities with osteoclasts [12]. Multinuclear odontoclast cells involved in internal inflammatory root resorption are equivalent to bone resorbing osteoclasts. Formed through the fusion of multiple monocyte or macrophage /precursors, osteoclasts are giant, multinucleated cells and are the only cell type that can resorb bone [7,13,14]. They contain large numbers of mitochondria and acidic vacuoles that carry acid phosphatases and other lysosomal enzymes. The rough endoplasmic reticulum is scant, and the Golgi apparatus consists of few flattened cisternae around the nuclei [15]
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