INTERNAL JUGULAR VEIN VALVE INSUFFICIENCY IN COUGH SYNCOPE

Abstract

A 53-year-old man with chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea was admitted to the hospital for the evaluation of recurrent syncopal episodes induced by paroxysmal cough. Loss of consciousness was brief, and preceded by the sensation of “fullness in the head.” Syncope was provoked also by prolonged expiration during spirometry, which revealed severe bronchial obstruction. However, oxygen saturation on room air and blood gases were within normal limits. To reproduce reported symptoms, the Valsalva maneuver (VM) was performed with the patient in the supine position with noninvasive, continuous blood pressure monitoring (Finapres, Ohmeda) and finger pulse oximetry. This resulted in a brief loss of consciousness, although no desaturation, decrease in blood pressure, or bradycardia was noted. Transthoracic echocardiography revealed normal left and right ventricular function, mild tricuspid insufficiency, and no evidence of pulmonary hypertension. There was no right-to-left shunt detected on the bubble-contrast study. Neurologic assessment, MRI of the brain, and EEG were unremarkable. Duplex-Doppler examination of extracranial carotid and vertebral arteries showed no stenosis. However, evaluation of the internal jugular veins (IJVs) with the use of color Doppler revealed right internal jugular valve insufficiency with flow reversal during inspiration (figure …