Abstract

Adult-onset Still's disease (AOSD) is a clinical syndrome characterized by long-term intermittent fever, transient polymorphic rash, arthritis or arthralgia, pharyngalgia, and accompanied by systemic involvements. The pathophysiology of AOSD has recently been classified as a complex autoinflammatory disease. Sometimes it is necessary to differentiate from coronary heart disease. In recent years, anakinra has been used to treat AOSD with promising results.

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