Abstract

Warthin’s tumour (WT), also known as the adenolymphoma, is the second common benign neoplasm that mostly occurs in the parotid gland. Malignant transformation of the epithelial or lymphoid component of the WT has been rarely reported. We describe a case of a 73-year-old woman who underwent total radical parotidectomy with modified neck dissection on the left side. The case was diagnosed as intermediate-grade mucoepidermoid carcinoma developed in the setting of WT based on histomorphologic findings. Clinical presentation, pathogenesis, differential diagnosis and management of the rare malignancy have been discussed briefly.

Highlights

  • Warthin’s tumour (WT) is a benign salivary gland neoplasm occurring principally in the parotid gland of men in the sixth and seventh decades of life [1,2,3,4,5]

  • Few cases of squamous, [2,3,4,5] adenocarcinoma [6,7,8,9] and mucoepidermoid carcinoma [10,11,12,13] arising in the setting of WT have been reported in the English language literature

  • We report a case of intermediate-grade mucoepidermoid carcinoma arising in WT of the parotid gland in a 73-yearold woman

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Summary

Introduction

Warthin’s tumour (WT) is a benign salivary gland neoplasm occurring principally in the parotid gland of men in the sixth and seventh decades of life [1,2,3,4,5]. Malignant transformation of the WT is rare and its reported incidence is 0.3% [1,2,3,4,5]. Few cases of squamous, [2,3,4,5] adenocarcinoma [6,7,8,9] and mucoepidermoid carcinoma [10,11,12,13] arising in the setting of WT have been reported in the English language literature. We report a case of intermediate-grade mucoepidermoid carcinoma arising in WT of the parotid gland in a 73-yearold woman.

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