Abstract
Histiocytoses are a heterogeneous group of disorders including: X, non-X, as well as the rare intermediate cell histiocytosis. This classification is based on clinicopathological as well as ultrastructural aspects. Intermediate cells belong to the dendritic cell group involved in antigen presentation to lymphocytes. These cells characteristically express S-100 and CD1a and lack Birbeck granules. We report a case of an 80 year old male with intermediate cell histiocytosis. This patient presented with multiple pruritic firm papules and nodules on the bilateral anterior lower extremities. An extensive systemic work-up revealed only a single lytic lesion in the skull. He received high potency topical steroids with good resolution of his pruritus, but with no effect on the cutaneous nodules. He has remained without systemic involvement after one year and the lytic lesion remained unchanged.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
