Abstract
As a novel interleukin-1 (IL-1) family member,IL-36 shares homologous amino acid sequence and similar signaling pathways with classical IL-1 family cytokines.A high expression of IL-36 is mainly observed on epidermal cells,dendritic cells and CD4+ T lymphocytes.IL-36 shows a stronger ability to regulate and activate immunoreaction than other IL-1 family cytokines,which may indicate a relatively more important role of IL-36 in immune response.Further more,it has been implied that IL-36 plays an essential role in the pathogenesis of autoimmune diseases such as systemic lupus erythematosus.Therefore,IL-36 maybe a promising molecule for future research into systemic lupus erythematosus. Key words: Lupus erythematosus, systemic; Autoimmunity; Interleukin-36
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Dermatology and Venereology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
