Abstract
To the Editor: Recently, we read with great interest the article titled “Increased Levels of Interleukin 34 in Serum and Synovial Fluid Are Associated with Rheumatoid Factor and Anticyclic Citrullinated Peptide Antibody Titers in Patients with Rheumatoid Arthritis,” published in The Journal of Rheumatology 1, showing that serum levels of interleukin 34 (IL-34) were positively correlated with rheumatoid factor (RF) and anticyclic citrullinated peptide antibody (anti-CCP) titers, but not with systemic osteoporosis and radiographic joint damage in rheumatoid arthritis (RA). Further, IL-34 levels were significantly increased in the serum of patients with RA (p < 0.001) or ankylosing spondylitis (p < 0.001) compared with controls2. These studies … Address correspondence to Dr. H. Wu, Department of Pharmacy, Binhu Hospital of Hefei City, The Third Affiliated Hospital of Anhui Medical University, 230001, Hefei, Anhui Province, China. E-mail: wuhuaedu{at}163.com
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