Abstract
Objective: The aim of this study was to evaluate whether the IL-1β gene could be a genetic marker of the thyroid-associated ophthalmopathy (TAO) development. Materials and Methods: The IL-1β gene polymorphisms at –511 and +3953 regions in 117 TAO patients of Polish origin (ATA/NOSPECS class III or greater) and in 106 controls were studied. Results: We found no significant differences in the frequencies of genotypes and allelic variants for SNP –511 and SNP +3953 between the controls and the studied groups. Conclusions: No association between the IL-1β polymorphisms and the TAO existed, so those polymorphisms are not suitable genetic markers for TAO.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
