Abstract

Abstract Twenty-six European laboratories have participated in a study of various methods used for determination of δ-aminolevulinic acid in urine, to determine to what extent they give comparable results when performed by different laboratories. None of the methods as used in the program appeared to be precise and accurate enough to allow each of several laboratories to detect the small differences in urinary δ-aminolevulinic acid that would result from differences in exposure to environmental lead. Variation among results obtained by different laboratories using the same technique probably reflects differences in the practical experience each laboratory had with the various techniques, rather than intrinsic problems with the methods themselves.

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