Abstract
Respiratory activities of OF 1 SPF male and female mice, in a LD 12:12 (L = 100 lux) lighting regimen and in controlled environmental conditions (temperature: 20–21°C; humidity: 60–70%), were compared, sexes apart, either separated or grouped by 10–11 individuals, by measuring their VCO 2 (continuous recording and measurement of CO 2 concentration with an accuracy of 20 ppm). In both sexes grouping increases D→L and L→D respiratory variations. VCO 2 per mouse has a higher level in separated than in grouped individuals of both sexes, a higher level in grouped males than in grouped females, and shows only a small sex-related difference in separated mice. Longevity of separated males and separated females does not differ statistically. Longevity is decreased by grouping in males but increased by grouping in females.
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