Abstract
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Highlights
In the 2014/15 influenza season, Canada has to date experienced early, intense influenza activity, with record numbers of long-term care facility outbreaks and a seasonal peak number of influenza-related hospitalisations, laboratory detections of influenza virus, and outpatient consultations for influenza-like-illness occurring in week 53 (28 December 2014 to 3 January 2015) [1]
99.0% (593/599 cases with known subtype) of hospitalisations for laboratoryconfirmed influenza enrolled in participating hospitals were due to influenza A; influenza A (H3N2) accounted for 99.1% (n=214) of the 216 cases with known subtype
Hospitalised patients with laboratory-confirmed influenza were older than test-negative controls (mean age: 77.7 years vs 70.9 (SD: 16.6) years, respectively; p < 0.001); 68.8% (n=413) of cases were over 75 years of age compared with only 44.8% (n=211) of test-negative controls (p < 0.001)
Summary
In the 2014/15 influenza season, Canada has to date experienced early, intense influenza activity, with record numbers of long-term care facility outbreaks and a seasonal peak number of influenza-related hospitalisations, laboratory detections of influenza virus, and outpatient consultations for influenza-like-illness occurring in week 53 (28 December 2014 to 3 January 2015) [1]. In the US, interim VE estimates demonstrate limited effectiveness of the 2014/15 vaccines in the prevention of laboratoryconfirmed, medically attended acute respiratory illness in persons of all ages, with adjusted VE estimates of 24% (95% confidence interval (CI): 0 to 43) in children aged 6 months to years, 16% (95% CI: −18 to 41) in adults aged to years and 23% (95% CI: −14 to 47) in adults aged years and older [2]. In Canada, the Sentinel Physicians Surveillance Network recently published interim estimates of VE against laboratory-confirmed, medically attended influenza A and influenza A(H3N2) of −4% (95% CI: −45 to 25) and −8% (95% CI: −50 to 23), respectively [3]. In Canada, annual influenza immunisation is recommended for all persons aged 6 months of age or older, with the primary goal of preventing influenza-associated hospitalisation and death [4].
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