Interhemispheric connectivity in congenital hemiparesis

Abstract

Aims: Early unilateral brain lesions can lead to different types of corticospinal (re-)organization. In some patients, the contralesional hemisphere exerts motor control over the (ipsilateral) paretic hand, as the primary motor cortex is (re-)organized in the contralesional hemisphere, whereas there are also patients with early unilateral lesions but normal contralateral motor projections. Here, we report on how cortical (re-)organization affects interhemispheric transcallosal connectivity in congenital hemiparesis.