Abstract
Sapovirus, a member of the family Caliciviridae, is an etiologic agent of gastroenteritis in humans and pigs. Analyses of the complete genome sequences led us to identify the first sapovirus intergenogroup recombinant strain. Phylogenetic analysis of the nonstructural region (i.e., genome start to capsid start) grouped this strain into genogroup II, whereas the structural region (i.e., capsid start to genome end) grouped this strain into genogroup IV. We found that a recombination event occurred at the polymerase and capsid junction. This is the first report of intergenogroup recombination for any calicivirus and highlights a possible route of zoonoses because sapovirus strains that infect pig species belong to genogroup III.
Highlights
Sapovirus, a member of the family Caliciviridae, is an etiologic agent of gastroenteritis in humans and pigs
We found that SW278 and Ehime1107 clustered into GII for the nonstructural region–based grouping but clustered into GIV for the structural region–based grouping
These results indicate that the nonstructural region of SW278 and Ehime1107, i.e., a GII sequence, did not belong to a distinct genogroup, unlike their structural region, which belonged to a distinct genogroup
Summary
A member of the family Caliciviridae, is an etiologic agent of gastroenteritis in humans and pigs. Analyses of the complete genome sequences led us to identify the first sapovirus intergenogroup recombinant strain. We found that a recombination event occurred at the polymerase and capsid junction. This is the first report of intergenogroup recombination for any calicivirus and highlights a possible route of zoonoses because sapovirus strains that infect pig species belong to genogroup III. The sapovirus (SaV) and norovirus (NoV) strains are etiologic agents of gastroenteritis in humans, animals such as pigs, cows, and mice can be infected. Using complete genome sequence analysis, we recently identified the first recombinant (intragenogroup) SaV
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
