Abstract

The effect of partially purified leukocyte (alpha) and fibroblast (beta)-derived interferons (IFNs) and crude immune (gamma) IFN on the transformation of non-T mononuclear leukocytes by the Epstein--Barr (EBV) virus was studied. The IFN preparations reduced the frequency of cells positive for EBV-specific nuclear antigen but did not significantly prolong the EBV-transformation interval.

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