Abstract
Interferon-associated retinopathy is a rare complication of interferon treatment. It has been well described with the use of interferon-α. This study reports a retrospective case series of interferon-β-associated retinopathy in three patients that were being treated for multiple sclerosis. All cases were characterized by cotton-wool spots or peripheral microaneurysms. One central retinal artery occlusion was observed associated with interferon-β treatment. Findings improved spontaneously in two of three cases; all three patients elected to continue interferon treatment. Patients being treated with interferon-β should have periodic fundus examinations to determine if they have evidence of interferon-associated retinopathy.
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