Abstract
level. Some newly active rate controlled electrically based transdermal techniques including: iontophoresis, electroporation, ultrasound and photomechanical waves have been developed and commercialized for the delivery of troublesome therapeutic protein and peptide based macromolecular drugs. This study covers the development of different electrically based transdermal techniques for delivery of therapeutic protein and peptide based macromolecular drugs, current status and assesses the pros and cons of each technique and summarises the evidence-base of their drug delivery capabilities.
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