Abstract
Sensitivity is an important parameter to characterize the performance of sensors. Interfacial modification and functionalization is an effective strategy to improve the sensitivity of optical biosensors. This paper reports our recent development on interface sensitized fiber optic biosensors for the detection of ultra-low concentration of biological targets. We employ microfiber mode interferometer as transducer to sense the molecular binding interaction induced surrounding refractive index change. By modifying the microfiber surface to increase the assembling surface area and enhance the evanescent field energy density, ultra-low limit of detection of 1.65 × 10−15 M and 6.82 × 10−17 M, respectively, were realized for neurotransmitter γ-amino-butyric acid and cellular cytochrome c.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callSimilar Papers
More From: Journal of Lightwave Technology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
