Abstract
With the advancement in nanopore (NP) technology, which enabled long-read nucleic acid sequencing, current research tries to extend this single-molecule technology towards proteomics. One of the biggest challenges in proteomics is the lack of protein amplification methods such as polymerase chain reaction in genomics and transcriptomics. This limitation is especially an issue if the protein of interest is only available in low concentrations as in the case for single-cell proteomics. Current available technologies are antibody-/cytometry- or mass spectrometry-based.
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