Abstract

A simple procedure is examined for forming a selective sensor coating using mixed self-assembling thiol monolayers functionalized by molecules of the sulfanilamide antibiotic, sulfamethoxazol (SMX). A model is proposed for the interface processes, which accounts for the complex dependence of the adsorption capacity of the coatings obtained on the surface density of the reactive groups and the low adsorption capacity at high reaction site concentrations. The model was supported by competitive inhibition analysis.

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