Interdependence between promitochondrial and cytoplasmic protein synthesis during respiratory adaptation in baker's yeast

Abstract

When anaerobically-grown yeast cells were aerated in the presence of cycloheximide, they accumulated intermediate(s) for respiratory adaptation. The formation of these intermediates was dependent upon promitochondrial protein synthesis and independent of cytoplasmic protein synthesis. The cytoplasmic system was unable to accumulate significant amounts of intermediates for adaptation in the absence of protein synthesis by the promitochondrial system.