Abstract
Background Biologic therapy has been used for over 10 years and is increasingly used in the treatment of many chronic inflammatory diseases. At the present time it has a very broad range of applications: rheumatic, dermatologic, gastrointestinal, neurologic and neoplastic diseases. Biologic therapy is represented by immunomodulator agents (antibodies or other peptides) that interfere with the regular humoral immune response. Thus, in addition to the beneficial effects in relation with the underlying disease it may lead to opportunistic infections: bacterial, viral, fungal, or parasitic.
Highlights
Biologic therapy has been used for over 10 years and is increasingly used in the treatment of many chronic inflammatory diseases
Intercurrent and opportunistic infections in patients treated with biological agents: study hypothesis
In addition to the beneficial effects in relation with the underlying disease it may lead to opportunistic infections: bacterial, viral, fungal, or parasitic
Summary
Biologic therapy has been used for over 10 years and is increasingly used in the treatment of many chronic inflammatory diseases. Intercurrent and opportunistic infections in patients treated with biological agents: study hypothesis Ramona Ștefania Popescu1,2*, Andra Bălănescu1,3, Adrian Streinu-Cercel1,2
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