Abstract

It is well known that men with balanced chromosomal rearrangement are at risk of producing chromosomally unbalanced gametes. However, it is not clear if the meiotic behavior of a balanced chromosomal rearrangement could affect the segregation of chromosomes not involved in the rearrangement (interchromosomal effect), leading to aneuploidy in the gametes. In this study, we investigated the existence of an interchromosomal effect in three heterozygous carriers of structural chromosomal rearrangements.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call