Abstract
RATIONALE: Recent studies in murine allergic rhinitis have demonstrated suppressive effects of either IL-5 deficiency or ML on eosinophil recruitment. Neither IL-5 deficiency nor ML alone, however, was sufficient to fully abrogate inflammation or symptoms, due to basophilia and cytokine redundancy in eliciting marrow responses (Saito et al, JI 2002;168:3017; Immunol 2001;104:226). We therefore investigated the combined effects of ML and IL-5 deficiency on in vivo tissue and marrow responses in this model.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
