Abstract
Non-ionic surfactant block copolymer of polypropylene glycol flanked by two blocks of polyethylene glycol known as pluronic. Pluronic F127 or poloxamer 407 is used to improve the solubility and enhance the bioavilability of many drugs. The interactions of pluronic F127 was studied in Rhodamine B dye and effects of inorganic cations through fluorescence data were observed. Fluorescence quenching were studied by series cations of salts viz CdSO4, MnSO4, ZnSO4, FeSO4, CuSO4 in the above system. Cu2+ was found to be extremely efficient quencher, Cd2+ and Fe2+ were moderate quenchers. Apart from fluorescence, lifetime, DLS, and SEM were used as characterization for the above study.
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