Abstract
1. 1. Total saponin fraction decreased the affinity of specific [ 3H]muscimol binding without changes in B max. Ginsenoside Rb 1 Rb 2, Rc, Re, Rf and Rg 1 inhibited the specific [ 3H]muscimol binding to the high-affinity site. 2. 2. Total saponin fraction increased the affinity of specific [ 3H]flunitrazepam binding. Ginsenoside Re and Rf enhanced specific [ 3H]flunitrazepam binding. 3. 3. Total saponin fraction decreased the affinity of specific [ 35S]TBPS binding without changes in B max. Ginsenosides did not affect specific or non-specific [ 35S]TBPS binding. 4. 4. Total saponin fraction decreased the affinity of specific [ 3H]baclofen binding without changes in B max. Ginsenoside Rc inhibited specific [ 3H]baclofen binding.
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