Abstract
A comprehensive longitudinal study would be essential in the analyses of psychological changes. At the National Institute for Longevity Sciences (NILS), a comprehensive longitudinal study of aging in Japan, the NILS Longitudinal Study of Aging (NILS‐LSA) started in November 1997. The participants of this study were 2300 residents aged 40–79 years who were random samples selected from the neighborhood area of the NILS. They were examined every 2 years at the NILS‐LSA Examination Center. From the recent results of the NILS‐LSA, interactions between health and psychological changes including mental effects of disease, relationship between physical health and cognitive function, and association of depression with nutrition and physical activity were shown.
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