Abstract
Abstract : A precise, reproducible, and sensitive serum neutralization test was developed to estimate Venezuelan equine encephalomyelitis (VEE) serum- neutralizing antibodies within 24 hours. The test is dependent on both the interactions of virus with antiviral serum and the resultant complex with anti- gamma globulin (IgG) antibodies. The 50% serum-neutralizing end point was calculated from the reduction of number of fluorescent cells in McCoy cell monolayers resulting from the neutralization of infective viral particles by antibodies. In comparative estimates of neutralizing antibodies of human and monkey sera, the sensitivity of the serum neutralization anti-IgG test was several hundred times greater than that of the conventional mouse serum neutralization test.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
