Interaction of Valine with Biometal Chlorides in an Aqueous Environment at 25°C

Abstract

Research in medical biology and pharmacology can expand understanding of the interactions of biometals with amino acids, which are key components of biological systems. This may lead to the development of new complexes that can be used in medicine, for example, to develop new drugs with antimicrobial activity or to maintain metabolic balance in the body. Research purpose:obtaining complex compounds of biometals, cobalt chloride, nickel chloride and manganese chloride with the amino acid valine, as well as the study of their physicochemical and biological properties. For the analysis, the Kjeldahl method was used to determine the nitrogen content. The composition of the formed crystals was analyzed by IR spectroscopy. The structure and shape of cobalt, nickel and manganese crystals were determined using a microscope. The identity of the obtained compounds was confirmed by IR spectroscopy and microscopic analyses. We can conclude that valine in the complex is coordinated to metal ions through the oxygen atoms of the carboxyl and nitrogen groups of the amine groups.