Abstract
The interaction of DNA bases and corresponding nucleotides with silver nanoparticles (AgNPs) biofunctionalized by tryptophan, has been investigated by absorption spectroscopy and dynamic light scattering. Aggregation of AgNPs was observed in the presence of ATP and GTP, in contrast to nucleoside. This is due to change in pH of the medium in the presence of triphosphates. Aggregation due to ATP was found to be greater than that of GTP, which is due to the interaction between adeninium ion and tryptophanyl residue on the surface of nanoparticle. There is a direct relationship between ATP concentration and aggregation of AgNPs, which in future might assist in developing new protocols for sensing of adenine nucleotides.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
