Abstract
Whereas neither blinding nor olfactory bulb removal alone appreciably altered the reproductive organs of adult female rats, when animals were subjected to both operations, the sexual organs were macroscopically and microscopically hypotrophic within 8 weeks; the frequency of pregnancy also was reduced greatly in the doubly deprived rats. Furthermore, adrenal and pituitary weights were characteristically smaller in rats deprived of their eyes and olfactory bulbs. Pinealectomy reversed all the effects which followed dual sensory deprivation. No statistically significant differences in the pineal levels of hydroxyindole- O-methyltransferase activity were found.
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