Abstract
The purpose was to ascertain whether Gram-positive bacteria derived from dental plaque could stimulate the release of lysosomal enzymes from rabbit peritoneal exudate polymorphonuclear leukocytes (PMNs). Microorganisms which were capable of inducing periodontal syndromes in experimental animals and of synthesizing extracellular polysaccharides were capable of triggering hydrolase release from PMNs. On the other hand, bacteria which did not produce extracellular polysaccharides under the conditions employed were relatively inactive in inducing a PMN-release response. Lysosome release resulting from bacterial-PMN interactions may be one important mechanism in the pathogenesis of gingivitis and periodontal disease.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
