INTERACTION OF EXERCISE AND DIET ON THE GLUCOSE AND LIPID METABOLISM OF WOMEN WITH NON-INSULIN DEPENDENT DIABETES MELLITUS (NIDDM)

Abstract

1000 The purpose of this study was to compare the effects of a high carbohydrate(HCHO) diet to a high monounsaturated fat (HMF) diet, combined with a daily one-hour low intensity walking program, on the glycemic and lipidemic control of 8 women with NIDDM. The HMF diet (CHO, 30%; fat, 53%; protein, 17%) and exercise program, and the HCHO diet (CHO, 64%; fat, 19%; protein, 17%) and exercise program, were each performed for a period of seven days. Both treatments resulted in a significant reduction of glucose (P<0.04). Body weight was also significantly reduced after the HMF treatment (P=.008). No significant changes occurred in lipid levels for either treatment. There were also no significant differences between treatments on the mean changes of glucose and lipid levels. Body weight was significantly lower after the HMF treatment (P=0.002) than the HCHO treatment. Results of the study revealed clinical differences in the subjects' metabolic responses between the two treatments. Glucose and triglycerides were reduced 16.5% and 28.8% after the HMF treatment. Total cholesterol and Low Density Lipoprotein (LDL-C) were reduced 4.5% and 4.8% after the HMF treatment, in contrast to a 1.5% and 8.4% elevation for the HCHO treatment. High Density Lipoprotein (HDL-C) increased by 5.6% after the HMF treatment in contrast to a reduction of 3.9% for the HCHO treatment. These preliminary findings suggest that a treatment of low-intensity aerobic exercise and a HMF diet may have a better effect on metabolism in women with NIDDM, compared to a HCHO treatment.