Abstract

Abstract In this paper, the physicochemical and photophysical properties of xanthene dyes interacting with micelles were evaluated. Xanthenes are potential photosensitizers for photodynamic therapy. The dyes were eosin Y and its ester derivatives with methyl, butyl and decyl alkyl groups. In aqueous media at physiological pH eosin is present as dianionic protolytic form while its esters are monoanionic. Analysis of the water/octanol partition coefficient showed that the eosin is the most hydrophilic compound and the hydrophobicity increases as the alkyl chain of the ester increases: eosin

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