Abstract

This study aimed to assess possible interactive effects of coping styles and psychological stress on depression and anxiety symptoms in Chinese women shortly after diagnosis of breast cancer. Four hundred and one patients with breast cancer were face-to-face interviewed by trained research staff according to a standardized questionnaire including information on socio-demographic characteristics, psychological stress, coping styles, and anxiety and depressive symptoms. Interactive effects were assessed by hierarchical multiple regression analyses. There were significant associations of the four domains of psychological stress with anxiety and depressive symptoms except for the relationship between "worrying about health being harmed" and depressive symptoms. "Abreaction coping behavior" and "escaping coping behavior" significantly increased the level of both anxiety and depressive symptoms; whereas an "active coping style" resulted in significant decrease. The interaction of "active coping behavior" with "worrying about health being harmed" significantly increased the risk of the anxiety symptoms, while adopting "self-relaxing coping behavior" was associated with significant decrease. The interaction of "worry about daily life and social relationship being restricted" with "escaping coping behavior" significantly increased the risk of the depressive symptoms. The results of this study suggest that certain coping styles might moderate the association of psychological stress with anxiety and depressive symptoms in Chinese women with breast cancer.

Highlights

  • Breast cancer is one of the most common malignancies affecting women (26% of all cancers) (Jemal et al, 2008)

  • This study aimed to assess the moderating effects of coping styles on anxiety and depressive symptoms caused by psychological stress originated from the diagnosis in Chinese patients with breast cancer

  • The results showed that psychological stress and coping styles might directly and interactively affect anxious and depressive symptoms in patients with breast cancer after controlling for potential confounding factors

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Summary

Introduction

Breast cancer is one of the most common malignancies affecting women (26% of all cancers) (Jemal et al, 2008). The diagnosis and treatment for breast cancer in women can cause significant psychological distress (Zabora et al, 2001; Massie et al, 2004), and bring about psychological disturbance including anxiety and depression (Pandey et al, 2006; Jacobsen et al, 2008). Anxiety and depression are the most frequently reported cancer-related symptoms. More than 30% of the women with early breast cancer had depression, anxiety, or both at diagnosis (Burgess et al, 2005). Numbers of studies reported that depressed patients tend to be less proactive in seeking more aggressive treatments, and have severe symptoms, poor response to systemic therapy, long recovery times and poor outcomes

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