Abstract

Morphology and morphometrical parameters of perikaryons and transcription activity of nuclear chromatin in neurons of cranial cervical sympathetic ganglion and in locus ceruleus are studied at different stages of ontogeny under conditions of desympathization and after selective damage to the locus ceruleus neurons induced by intracysternal injection of 6-hydroxydopamine. It is shown that the magnitude and direction of changes in neuronal ultrastructure and activity of protein-synthesizing apparatus varies during ontogeny and depends on the integral state of catecholaminergic neurons.

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