Abstract
Thyroglobulin liposome was prepared from egg yolk lecithin, dicetylphosphate, cholesterol and thyroglobulin. The liposomal fraction was separated by Sephadex G-75 column after Pronase treatment. Rate of hydrolysis of liposomal thyroglobulin by lysosomal fraction obtained from thyroid glands was around twice the value of thyroglobulin solution hydrolyzed by the same fraction. This result might suggest that thyroglobulin covered with lipid layer(s) is in a favourable condition for hydrolysis by lysosomes.
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