Abstract
A basic model of the interaction between membrane ion-transferring systems in smooth muscle cells is developed in this work. The permanent ion exchange through a cell membrane is proposed to be maintained by the interplay between a potential-dependent Ca 2+ channel, an electrogenic 3 Na +/Ca 2+ antiporter, a Na + K + pump a K + channel. It is shown that the 3 Na +/Ca 2+ exchange mechanism can play a major role in the steady self-oscillation of the membrane potential in smooth muscles.
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