Abstract
Abstract Imipramine-like drugs potentiate the hyperthermic response obtained by infusion of noradrenaline, adrenaline and isoprenaline. In addition to this effect, desipramine increases the hyperthermic response induced by L-dopa (in monoamine oxidase blocked rats), reserpine (immediately after intravenous injection) and dexamphetamine. On the contrary, other types of hyperthermia, such as the one induced by phenethylamine in monoamine oxidase treated rats, and that by yeast, were not increased by desipramine. These results are discussed in relation to the mechanism of action of antidepressant drugs.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
