Interacting ventral temporal gradients of timescales and functional connectivity and their relationships to visual behavior

Abstract

Cortical gradients in endogenous and stimulus-evoked neurodynamic timescales, and long-range cortical interactions, provide organizational constraints to the brain and influence neural populations' roles in cognition. It is unclear how these functional gradients interrelate and which influence behavior. Here, intracranial recordings from 4,090 electrode contacts in 35 individuals map gradients of neural timescales and functional connectivity to assess their interactions along category-selective ventral temporal cortex. Endogenous and stimulus-evoked information processing timescales were not significantly correlated with one another suggesting that local neural timescales are context dependent and may arise through distinct neurophysiological mechanisms. Endogenous neural timescales correlated with functional connectivity even after removing the effects of shared anatomical gradients. Neural timescales and functional connectivity correlated with how strongly a population's activity predicted behavior in a simple visual task. These results suggest both interrelated and distinct neurophysiological processes give rise to different functional connectivity and neural timescale gradients, which together influence behavior.