INTER-OBSERVER AGREEMENT OF PI-RADS SCORE VERSION 2 FOR PROSTATE CANCER

Abstract

Objective:To assess the inter-observer agreement with the use of the Prostate Imaging Reporting and Data System (PI-RADS) version 2.0 for detection of prostate cancer at multiparametric magnetic resonance (MR) imaging in a tissue diagnosis patient population. Material and Method:This retrospective study was approved by the local ethics committee. Fifty-six lesions in 37 patients with elevated prostate-specific antigen levels who underwent trans-rectal ultrasound (TRUS)-guided biopsy or prostatectomy with multiparametric MR imaging of the prostate suspicious lesions detected at multiparametric MR imaging were scored by four readers of varying experience who were blinded to pathologic results by using to the newly revised PI-RADS and the scoring system version 2. Inter-observer agreement was evaluated by using the Intra-Interclass Correlation Coefficient (ICC). Results: Inter-observer agreement of four observers using the PI-RADS v2 for prostate cancer was an intermediate to good agreement beyond chance; ICC = 0.736, (95% CI: 0.565, 0.851). All observers, there was a most correlated PI-RADS assessment between observer 1 and observer 2 r = 0.758 (p<0.001). Conclusion: PI-RADS score version 2 shows intermediate to good agreement in readers of varying experience.