Abstract
Common variable immunodeficiency (CVID) affects approximately 1 in 30,000 individuals and is caused by defective B cell differentiation. Clinical presentations and laboratory anomalies guide the diagnosis of CVID. Given switched memory B cell levels below 70% of the related age adjusted reference interval are considered consistent with CVID, we sought to assess the performance of laboratories in the B cell subsets program offered by RCPAQAP.
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