Abstract

One of the biggest sources of dread for patients and a top concern for dentists is the anticipation and reality of root canal-related pain.1 Pain is defined as "an unpleasant sensory and emotional experience associated with actual or potential damage or described in terms of such damage" by the International Associates for the Study of Pain.2 The imbalance in the host-bacteria connection brought on by intra canal operations is the main cause of inter appointment pain. Objectives: The goal of current study was to associate the outcomes of these intracanal medications on pain experienced between endodontic appointments. This would make it easier for us to find better medications to treat discomfort between appointments. Methodology: For a period of six months, from January 6, 2022, to January 1, 2023, this randomized controlled study was carried out in the Dept. of Operative Dentistry at the MIHS in Islamabad, Pakistan. With a 5% level of significance, an 85% power of the trial, and a fraction of effectiveness of 72% with triple antibiotic paste and 38% with calcium hydroxide, a sample size of 80 people, 40 in each group, was estimated.

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