Abstract
SummaryIntensive nursing (6 pups/6 intact abdominal-inguinal mammary glands, and replacing all 16-day-old litters every 4 days with 12-day-old foster litters) failed to prevent significant declines in mammary DNA, RNA, and litter weight gains between days 20 and 36 of lactation. But no comparable changes in lactic acid content of mammary glands were observed. Intense nursing maintained pituitary prolactin during extended lactation but ACTH decreased 67.6%. Thus, ACTH may be rate limiting to milk synthesis during extended lactation.
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