Abstract

Lipopolysaccharide complex of typhoid bacilli was injected intravenously to chinchilla rabbits. The dose of the antigen was titrated according to the pyrogenic effect and the capacity for inducing the antibody production. Each rabbit received a stimulating antibody-producing dose of 15 γ and an immunizing dose of 3.5–5 γ of the antigen per kg of the animal's body weight.

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