Intelligent Internet of Things in Mammography Screening Using Multicenter Transformation Between Unified Capsules

Abstract

Mammography screening is one of the important applications for the intelligent Internet of Things (IoT). Due to the efficient and personalized cyber-medicine system, early diagnosis can successfully reduce the breast cancer mortality rate by AI-driven healthcare. However, it is a huge challenge to extend the conventional single-center into the multicenter mammography screening, thus improving the effectiveness and robustness of intelligent IoT-based devices. To address this problem, we utilize multicenter mammograms by the modified capsule neural network and propose a novel framework called multicenter transformation between unified capsules (MLT-UniCaps) in this article. The proposed MLT-UniCaps is composed of Attentional Pose Embedding, Dynamic Source Capsule Traversal, and Adaptive Target Capsule Fusion to realize an intelligent remote assistant diagnosis. Attentional Pose Embedding extracts feature vectors via variations in position, orientation, scale, and lighting as the poses through an adversarial convolutional neural network with an attention-based layer. Based on the pose presentation, Dynamic Source Capsule Traversal deploys a dynamic routing mechanism between neurons to build a source cancer classifier for single-center mammography screening. Using the source cancer classifier, Adaptive Target Capsule Fusion integrates various centers of mammograms as the universal cancer detectors and optimizes heterogeneous distribution among them by the transformation-likelihood maximization. Owing to the three components, MLT-UniCaps effectively improves the results of single-center mammography screening and works in the multicenter breast cancer diagnosis. By comprehensive experiments on 58 965 samples, the proposed MLT-UniCaps obtains 90.1% of overall classification accuracy on single-center trials and 73.8% of overall F1 score on multicenter trials. All the experimental results illustrated that our MLT-UniCaps, an intelligent IoT-based clinical tool, inures the benefit of mammography screening.