Abstract
Neuroscience The brain constantly integrates enormous amounts of information. While dynamically synthesizing cognitive processes as a function of an everchanging environment, the brain must stay flexible enough to adapt to continuous challenges. Shine et al. used a sophisticated computational framework to analyze functional magnetic resonance imaging data obtained during a wide range of cognitive tasks. They found a large integrative core of interconnected brain regions that processes information and optimizes cognitive performance and that also correlates with fluid intelligence. When the brain needs to work on more specific tasks, this integrative network segregates into more-specialized, regional brain activity. Altering neurotransmitter activity by pharmacological manipulation or disease could modulate these dynamics and affect cognitive performance. Nat. Neurosci. 22 , 289 (2019).
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