Integration of simultaneous fMRI and EEG source localization in emotional decision problems

Abstract

Simultaneous EEG-fMRI has been a powerful technique to understand the mechanism of the brain in recent years. In this paper, we develop an integrating method by integrating the EEG data into the fMRI data based on the parametric empirical Bayesian (PEB) model to improve the accuracy of the brain source location. The gambling task, a classic paradigm, is used for the emotional decision-making study in this paper. The proposed method was conducted on 21 participants, including 16 men and 5 women. Contrary to the previous method that only localizes the area widely distributed across the ventral striatum and orbitofrontal cortex, the proposed method localizes accurately at the orbital frontal cortex during the process of the brain's emotional decision-making. The activated brain regions extracted by source localization were mainly located in the prefrontal and orbitofrontal lobes; the activation of the temporal pole regions unrelated to reward processing disappeared, and the activation of the somatosensory cortex and motor cortex was significantly reduced. The log evidence shows that the integration of simultaneous fMRI and EEG method based on synchronized data evidence is 22,420, the largest value among the three methods. The integration method always takes on a larger value of log evidence and describes a better performance in analysis associated with source localization. Data availabilityThe data used in the current study are available from the corresponding author upon on reasonable request.