Integration of Mitochondrial Function

Abstract

Diffusional Integration of Mitochondrial Function.- Diffusional Integration of Mitochondrial Function: Lateral Diffusion of Proteins in Energy Transduction.- Diffusion and Collision in Cytochrome c-Mediated Electron Transport.- Is Electron Transfer Mediated by Random Diffusion Alone?.- Role of Ubiquinone Diffusion in Mitochondrial Electron Transfer.- Physical Constraints on Lateral Diffusion and Ubiquinone-Mediated Mitochondrial Electron Transport.- Inhibition of Bovine Heart Mitochondrial NADH - Ubiquinone Reductase by Tinopal AN, A Cationic Benzoxazole.- Topographical Changes in Cytochrome C Oxidase in the Soluble and Membrane-Bound Enzyme as Probed by Antibodies to Subunit V and the Whole Enzyme.- Multiple Forms of Cytochrome C Oxidase Observed in Heart Tissue, Myocytes, and Mitochondria by Fourier Transform Infrared Spectroscopy.- Functional Importance of Mitochondrial Cardiolipin in Yeast Cytochrome c Oxidase Activity.- Lateral Diffusion of Mitochondrial F1F0ATP Synthase: A Random Collision Model for Proton Transfer and ATP Synthesis.- Thermodynamic Integration.- Thermodynamics and Control of Proton-Motive Free-Energy Transduction.- The Mechanism of Uncoupling of Oxidative Phosphorylation.- Upper and Lower Limits of Charge, Proton and ATP Stoichiometries of Oxidative Phosphorylation.- ATP/2e? Stoichiometries for the Coupling Sites of Mitochondrial Oxidative Phosphorylation: Evaluation by Equilibrium and Non-Equilibrium Thermodynamics.- Nonequilibrium Thermodynamics and Cellular Bioenergetics.- The Near-Equilibrium Thermodynamics Approach to Living Systems.- The H+/e? Forces and Stoichiometries of the Mitochondrial Respiratory Chain.- Variation of Efficiency with Free Energy Dissipation in Theoretical Models of Oxidative Phosphorylation and Cytochrome Oxidase.- Analysis of Mechanisms of Free Energy Coupling and Uncoupling by Inhibitor Titrations.- Flux Control and Structural Regulation.- Mechanisms Stabilizing the Protonmotive Force in Respiring Mitochondria.- Regulation of Respiration and Pyruvate Dehydrogenase in Isolated Cardiac Myocytes and Hepatocytes.- Control Analysis of Cellular Metabolism: Application to Gluconeogenesis in Rat-Liver Cells.- Mitochondrial Volume Control.- Organization of the Mitochondrial Matrix.- Competition Between Electron Transfer and ATPase in Generating Steady-State Protonmotive Force and Phosphorylation Potential.- Control of Respiration and ATP Hydrolysis in Uncoupled Mitochondria.- Voltage-Dependent Channels are Present in the Inner Membrane of Mitochondria.- The Kinetics of Inorganic Phosphate Uptake and Utilization by Chick Heart Mitochondria.- Possible Role of Membrane-Enzyme Interactions in Activation of Pyruvate Carboxylation and Decarboxylation in Mitochondria.- Duramycin Effects on Mitochondrial Structure and Function.- Mitochondrial Compartmentation of Branched Chain Amino Acid Catabolism: Is the Aminotransferase A Mitochondrial Enzyme?.- Mitochondrial Lactate Dehydrogenase.- Lithium Ion is a Competitive Inhibitor of the Na+ Selective Na+/H+ Antiporter from Mitochondria.- In Situ Assessment of Mitochondrial Function.- Mitochondrial Membrane Potential and pH Gradient in Hypoxic Hepatocytes: Characteristics of the Neahypoxic State.- Blebbing, Cytosolic Free Calcium, and Mitochondrial Membrane Potential Following Toxic and Anoxic Injury in Hepatocytes.- Physiological Significance of a New Adenine Nucleotide Transport Mechanism in Liver Mitochondria.- Integration of Mitochondrial Function with High Aerobic Glycolysis in Tumors: Role of Hexokinase Binding to the Outer Mitochondrial Membrane.- Cytosolic Free Calcium and Myocardial Cell Injury.- Relationships Between Extracellular pH, Intracellular pH, and Cell Injury During `Chemical Hypoxia'.- Regulation of the Mitochondrial ATPase In Situ in Slow and Fast Heart-Rate Hearts.- The Role of Ionized Cytosolic Calcium ([Ca2+]i) in Acute and Chronic Cell Injury.- Succinate and Oxygen Dependence of Mitochondrial Function in Neonatal Hepatocytes.- Cyclic Nucleotides and Mitochondrial Functions at Birth.- Simultaneous Determination of Proton Concentration in Two Compartments.- Tetraphenylphosphonium Ion Distribution in Human Fibroblasts as a Function of In Vitro Aging.- Hormones and Calcium.- The Role of Calcium in the Control of Cell Function.- Hormonal Control of Ca2+-Sensitive Intramitochondrial Enzymes in Mammalian Tissues.- Effect of Mitochondrial Ca++ on Hepatic Aspartate Formation and Gluconeogenic Flux.- Glucagon Stimulation of Mitochondrial Metabolism.- The Function of the Uncoupling Protein in the Intact Brown Fat Cell.- Hormonal Regulation of the Hepatic 2-Oxoglutarate Dehydrogenase Complex.- Ca2+-Dependent NAD(P)+-Induced Alterations in Membrane Permeability of Rat Liver Mitochondria.- Integrated Mitochondrial and Microsomal Regulation of Free Ca2+ in Permeabilized Insulinoma Cells.- The Estimation of the In Vivo Mitochondrial Free Ca2+ Concentration.- Intercellular Integration of Energy-Linked Metabolism.- Metabolic Zonation of Carbohydrate Metabolism in the Liver.- Acinar Compartmentation of Amino Acid and Ammonia Metabolism and Its Functional Significance.- Role of Mitochondria in Zone-Specific Toxicity to the Liver Lobule.- Role of Calcium in Regulation of Hepatic Oxygen Uptake.- Heterogeneity of Energy Metabolism in the Kidney.- Metabolic Key to Hypoxia Tolerance: Loss of Regulatory Links Between the Electron Transfer System and Glycolysis.- Glucagon Actions in Perfused Liver are Oxygen Dependent.- Microzonation of Metabolism Associated with Mitochondrial Distribution in Cells.