Abstract
Historically, the metaphase chromosome and its architecture has been viewed as the ultimate representation of a non-functional inactive chromatin state. Recent studies of centromere (kinetochore) function in concert with studies of the placement and function of several classes of chromosomal proteins now call for a reevaluation of this view. In this article a model of chromosome structure with functional correlates is presented. Evidence for the existence of a functional chromosomal region, the "Surface Domain" is discussed.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
