Abstract
Background Peripheral arterial disease (PAD) is accompanied by a complex lower limb pathophysiology resulting in reduced functional capacity and quality of life. We aim to characterize the exercise recovery kinetics in the calf muscle of healthy volunteers by combining treadmill exercise and magnetic resonance (MR) relaxometry (T1, T2 and T2*), and to investigate their relation with age and treadmill exercise duration.
Highlights
Peripheral arterial disease (PAD) is accompanied by a complex lower limb pathophysiology resulting in reduced functional capacity and quality of life
Peak exercise, peak-rest difference, end of exercise recovery and decay rate values was checked against age and exercise test duration using Pearson’s correlation
We investigated treadmill exercise induced changes in normal calf muscles, and showed the exercise induced response can be quantified by magnetic resonance (MR) relaxometry, and is age and exercise duration dependent
Summary
Integrated treadmill stress testing and MR relaxometry (T1, T2, T2*): response in healthy calf muscles. Juliet Varghese1,2*, Debbie Scandling, Jason Craft, Subha V Raman, Orlando P Simonetti, Georgeta Mihai. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. 16-19 January 2014
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